As a sea monster lunges towards her, the nude Andromeda recoils, straining against the chains that tie her to the rocky ledge. Her hair blows behind her, indicating sudden movement. The sharp angles of her eyebrows and nose express anxiety, while the diagonal of her body expresses the repulsion she feels towards the growling beast.

Andromeda and the Sea Monster depicts a dramatic moment from the ancient Greek author Euripides' tale of Andromeda and Perseus. Andromeda's mother angered the gods with her boast that Andromeda was more beautiful than the Nereids, the attendants of the god of the sea, Poseidon. To appease the offended Poseidon, who threatened to destroy their entire kingdom, Andromeda's parents sacrificed their daughter by leaving her where she would be devoured by his monster. As Andromeda awaits the monster, chained to a rock, Perseus flies overhead, falls instantly in love with her, and rescues her by slaying the beast. Massimiliano Soldani Benzi's interpretation of the story is unusual because he focused on Andromeda's horror at the monster instead of on her rescue.